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Index > Protein center > Pola2(Gene name) > Rat
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  • Pola2 (Gene name),
  • DNA polymerase alpha subunit B (Protein name ),  DPOA2_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Pola2;
    Protein name:
    DNA polymerase alpha subunit B;
    Alternative:
    DNA polymerase subunit II;DNA polymerase alpha 70 kDa subunit;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    DNA polymerase alpha:primase is a four subunit enzyme complex, which is assembled throughout the cell cycle, and consists of the two DNA polymerase subunits A and B, and the DNA primase large and small subunits. Subunit B binds to subunit A.
    Function:
    May play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    600
    Sequence:
    50:
    MAVSTQQLAE | ELQIFGLDCE | DSLLEKLAEL | CTLYRQTEER | MVSELIAFCT | 
    100:
    SAGKSCLTGE | ILSSFEHEVL | NKKLSKACHS | ASKDNRHAGA | RDIVSIQELI | 
    150:
    EAEEEEETLL | SAYTTPSKGP | HKRVSSTPET | PLTKRSISTR | SPHQLLSPSS | 
    200:
    FSPSATPSQK | YSSRTNRGEV | VTTFGSAQGV | SWSGRGGSGS | ISLKVMGYPE | 
    250:
    PLTSSYKTMF | QQLPDIREVL | TCKIEELGSE | LKEHYKIEAF | TPLLVPAQEP | 
    300:
    VILLGQIGCD | SNGRLNSKSV | ILEGDREHSS | GAQIPVDVSE | LKDYSLFPGQ | 
    350:
    VVIMEGFNTT | GRRLTATKLY | EGVPLPFYQP | TEEEGDFEQT | MVLVACGPYT | 
    400:
    TSDSITYDPL | LDLISTINHD | RPDVCILFGP | FLDAKHEQVE | NCKLTSPFED | 
    450:
    IFKQCLRTVI | EGTRSSGSHL | VFVPSLRDVH | HEPVYPQPPF | TFSELPREDK | 
    500:
    KRVQFVSEPC | NLSINGVMFG | LTSTDLLFHI | GAEEICSSSG | TSDRFSRILK | 
    550:
    HILTQRSYYP | LYPPHEDMAI | DYENFYTYAQ | LPVTPDVFIV | PSELRYFVKD | 
    600:
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat DNA polymerase alpha subunit B
    Cat.:
    E14346r
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Rat DNA polymerase alpha subunit B
    Cat.:
    E14346h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat DNA polymerase alpha subunit B
    Cat.:
    E14346m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Rat DNA polymerase alpha subunit B
    Cat.:
    E14346b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat DNA polymerase alpha subunit B
    Cat.:
    U14346h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat DNA polymerase alpha subunit B
    Cat.:
    U14346m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat DNA polymerase alpha subunit B
    Cat.:
    U14346b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat DNA polymerase alpha subunit B
    Cat.:
    U14346r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Rat DNA polymerase alpha subunit B
    Cat.:
    P14346Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat DNA polymerase alpha subunit B
    Cat.:
    P14346Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat DNA polymerase alpha subunit B
    Polyclonal Antibody for Rat DNA polymerase alpha subunit B
    Cat.:
    P14346Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat DNA polymerase alpha subunit B
    Monoclonal Antibody for Rat DNA polymerase alpha subunit B
    Monoclonal Antibody for Rat DNA polymerase alpha subunit B
    Monoclonal Antibody for Rat DNA polymerase alpha subunit B
    Protein for Rat DNA polymerase alpha subunit B
    Protein for Rat DNA polymerase alpha subunit B
    Protein for Rat DNA polymerase alpha subunit B
    Protein for Rat DNA polymerase alpha subunit B

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    Precision
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    Linearity
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    References
    1. 1.
      "A mutation in subunit B of the DNA polymerase alpha-primase complex from Novikoff hepatoma cells concomitant with a conformational change and abnormal catalytic properties of the DNA polymerase alpha-primase complex."
      Popanda O. , Flohr C. , Dai J.C. , Hunzicker A. , Thielmann H.W.
      Mol. Carcinog.31:171-183(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Sprague-Dawley.
      tissue: Liver.
    2. 2.
      "A mutation detected in DNA polymerase delta cDNA from Novikoff hepatoma cells correlates with abnormal catalytic properties of the enzyme."
      Popanda O. , Flohr T. , Fox G. , Thielmann H.W.
      J. Cancer Res. Clin. Oncol.125:598-608(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 106-600
      strain: Sprague-Dawley.
      tissue: Liver.
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